Cannabidiol, or CBD, is the main component of cannabis. It is present in the resinous flower, accounting for up to 45% of the plant's extract. CBD is one of more than 100 cannabinoids unique to the cannabis plant.

It is a natural, non-psychoactive or psychotropic compound with enormous therapeutic potential. Researchers are trying to elucidate its properties and its ability to improve symptoms.

Cannabis oil rich in CBD is used as a dietary supplement, topical remedy or pharmacological treatment for the relief of chronic pain, inflammation in inflammatory bowel or skin diseases, anxiety, depression or the severity and frequency of seizures in refractory epilepsies.

It is also used to treat symptoms of neurological or neuropsychiatric diseases such as multiple sclerosis, Alzheimer's, Parkinson's or schizophrenia. Together with the other most studied cannabinoid, THC, it has been shown to induce cancer cell death. in vitro e in vivo in animal models, inhibiting tumor progression.

We still do not know all the medicinal qualities of the CBD and much research remains to be done, although so far there is evidence of properties:

• Analgesics
• Anxiolytics
• Neuroprotective
• Antipsychotics
• Anticonvulsants
• Antitumor

According to clinical studies, this provides it with therapeutic value or potential for the following pathologies

Chronic pain.

Chronic Inflammatory Skin Diseases: ( dermatitis, psoriasis and acne ).

Neurological Disorders(Alzheimer's disease (AD), dementia, Parkinson's disease (PD) and other movement disorders, multiple sclerosis, epilepsy-refractory epilepsy or cerebrovascular accident (CVA).

Inflammatory Bowel Diseases (IBD): ( Crohn's disease and ulcerative colitis )

Anxiety, Stress and Depression.
Cardiovascular disorders.

Cancer: brain tumors (gliomas), of Leather (melanoma and skin carcinoma), breast, pancreatic, liver and prostate carcinoma, among others; in palliative treatment, it improves chemotherapy symptoms such as physical pain, nausea, vomiting and insomnia.)

Metabolic Syndrome(obesity and diabetes).

Autoimmune Inflammatory Diseases  ( fibromyalgia arthritis )

Neuropsychiatric Diseases
(schizophrenia, autism, attention deficit hyperactivity disorder (ADHD), post-traumatic stress disorder (PTSD) and alcoholism.

No. Cannabis contains more than 500 organic compounds, of which at least 113 are cannabinoids.

Among these cannabinoids, the following stand out due to their therapeutic qualities CBD and the THC.

East, the tetrahydrocannabinolis the predominant psychotropic compound in the plant, responsible for the psychoactivity for which cannabis is known.

CBD does not have psychoactive effects; THC does. But both have a very significant therapeutic value, which is enhanced when they "work" together; a synergistic effect is produced: CBD enhances certain properties of THC, such as analgesic or anti-cancer properties, while counteracting its psychoactivity.

There are many clinical studies that demonstrate the active ingredients and benefits of the cannabidiol or that are trying to reveal new medicinal properties -Curativas o Paliativas- of cannabinoids in diseases.

Preclinical and clinical studies evaluating the efficacy and safety of CBD isolated from cannabis plants played an essential part in the approval of the first medicine Epidiolex ® which is used to treat certain refractory epilepsies in children.

In addition to medicines, CBD products are also continually tested for other purposes, such as skin health and improving the condition of certain common skin conditions, including acne, eczema, insect bites and even psoriasis. A recent study by Laura Casares and colleagues (2020) revealed that topical use of CBD helps improve the appearance of skin conditions such as atopic dermatitis and keratin disorders. Another study conducted by Hammell and colleagues (2016) reported effective pain relief after topical administration of CBD products, in particular the use of CBD-infused gel.

CBD dosage recommendations

How many mg of CBD do I need? 

• The amount of CBD needed for each person is very personal and variable. There are many factors that can modify the effect of CBD, such as weight and size, but also more complex ones, such as metabolic and pathophysiological differences. 
• Even variables as subjective as the sensation that each person feels when taking CBD oil come into consideration. Two physically similar people may use different doses of CBD. Sometimes, even the same dose in the same person can have different effects depending on the day. 
• It is always advisable to start with low doses, regardless of the concentration of CBD oil. Some people feel that the effects are negligible. Even so, we insist on maintaining the dose for 1 week before increasing it, since the effects of CBD may still be acting, although we do not appreciate them at the beginning. 

How do I know what concentration of CBD oil to buy? 

In general, to choose the concentration of CBD oil we are guided by: 

• Weight and height: the more body mass, the more CBD will be needed, relatively speaking. It is also not necessary to buy the highest concentration CBD oil, but we would initially think of a medium concentration. Likewise, a large person may feel that a lower concentration oil works for them. 
• Experience in the use of CBD: we advise to reserve CBD oils of higher concentrations for people who are already familiar with their effects. 
• Ailment to be treated: if CBD is required in high doses as an anti-inflammatory or analgesic, it may be necessary to go to medium or high concentrations. We recommend that you consult with a specialist to assess your case. personally. 

CBD content: 

• CBD Oil 30%: Each spray contains 15 mg. of CBD. 
• CBD Oil 20%: Each spray contains 10 mg. of CBD. 
• CBD oil 10%: Each spray contains 5 mg. of CBD. 

• These products are sold in pharmacies in Switzerland, Belgium, Germany, Luxembourg and Spain.

• They are organic products, that is to say, the CBD used to elaborate them comes from the extraction with CO2 of flower and organic biomass, unlike 99% of the existing products in the Spanish market that come from synthetic CBD elaborated in laboratory and without existence of organic raw material.
• All products distributed by Agrocult are manufactured with raw materials that have GMP and GACP certifications.
• All our products include in the packaging the manufacturing batch number with which you can access the laboratory test of each batch, including in this updated analysis the levels of CBD, THC, CBG and other cannabinoids. This guarantee is not provided by any of the products we have tested in the Spanish market.
• Each product we distribute includes in its packaging the amount in Mg of real CBD it contains.
• All the products we distribute have passed the most demanding laboratory and clinical tests before being made available to users.
• The raw materials used (hemp Sativa L) that guarantee the ORGANIC production in all our products come from organic outdoor and indoor crops in Switzerland and Germany, complying with all the strict governmental quality and traceability controls of those countries. Most of the products for sale in Spain that boast of being organic come from crops in Eastern countries, Italy, Portugal, etc... where quality controls are scarce or non-existent, thus not being able to guarantee the traceability of the final product.